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We conducted an experiment where we substituted all 7 asparagine residues in the cystinosin lumen (i.e., the putative N-linked glycosylation sites) with alanine, creating the 7NA mutant

Readers exploring broader microbiome support may also want to review Akkermansia for gut health, especially when considering how gut barrier support, microbial balance, and metabolic signaling may relate to menopause wellness

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CGS catalyzes the formation of cystathionine from homoserine and cysteine 32 and its absence in egtA 26933 suggests that cystathionine production is attenuated when EGT biosynthesis cannot occur, perhaps to provide cysteine in order to increase GSH production